
About Episteme Prognostics, Inc.
Episteme Prognostics, Inc. was founded in 2021 as a spin-out from Memorial Sloan Kettering Cancer Center (MSKCC) and Dartmouth Cancer Center.
Our founders, Surajit Dhara, PhD, and Steven D. Leach, MD, identified a tumor-cell-intrinsic gene regulatory pattern in pancreatic cancer strongly associated with chemotherapy response. This discovery opened a new approach to understanding how cancer cells respond to treatment and potentially develop resistance.
We began with pancreatic cancer, one of the most aggressive malignancies with extremely limited precision medicine options. These early findings became the foundation of Episteme’s scientific mission.
Today, we are advancing PancEpistemeDx™, our first diagnostic, while building a platform with broad potential across cancer therapies and biopharma development.



